Starring: Andy Samberg, Jeff Daniels, Cheryl Hines, Kenan Thompson, Stanley Tucci, Kristin Chenoweth, Patrick Warburton
Directed by: Kirk De Micco
Produced by: Barry Sonnenfeld, John H. Williams, John W. Hyde
Written by: Kirk De Micco, Robert Moreland

Ham III, the grandson of the first chimp astronaut, is blasted off into space by an opportunity-seeking senator. Soon, the fun-loving chimp has to get serious about the mission at hand: Rid a far-away planet of their nefarious leader. Fortunately for Ham III, two of his simian peers are along for the ride.